This is named after its discoverer, the German anatomist Johann Georg Wirsung (1589–1643). The pancreatic duct is also called the duct of Wirsung. Pancreatic ductal carcinoma is a common form of pancreatic cancer. Pancreatic duct or parts of pancreatic duct can be demonstrated on ultrasound in 75 to 85% of people. The pancreatic duct is generally regarded as abnormally enlarged if being over 3 mm in the head and 2 mm in the body or tail on CT scan. Bile backing up into the pancreatic duct may initiate pancreatitis. A gallstone may get lodged in the constricted distal end of the ampulla of Vater, where it blocks the flow of both bile and pancreatic juice into the duodenum. Obstruction can also be due to duodenal inflammation in Crohn's disease. The most common cause for obstruction is the presence of gallstones in the common bile duct, a condition called choledocholithiasis. įormation of an accessory pancreatic ductĬompression, obstruction or inflammation of the pancreatic duct may lead to acute pancreatitis. It is named for Giovanni Domenico Santorini. The main pancreatic duct and the accessory duct both eventually-either directly or indirectly-connect to the second part ('D2', the vertical segment) of the duodenum. In the other 30% of people, it drains into the main pancreatic duct, which drains into the duodenum via the major duodenal papilla. It may open separately into the second part of the duodenum, which is dorsal, and usually (in 70% of people) drains into the duodenum via the minor duodenal papilla. An accessory pancreatic duct can be functional or non-functional. However, some have an additional accessory pancreatic duct, also called the Duct of Santorini. Most people have just one pancreatic duct. There are many anatomical variants reported, but these are quite rare. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla.
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